Article
Principal components of heritability from neurocognitive domains differ between families with schizophrenia and control subjects.
Schizophrenia bulletin - 1 Mar 2013
Wiener Howard, Klei Lambertus, Calkins Monica, Wood Joel, Nimgaonkar Vishwajit, Gur Ruben, Bradford L DiAnne, Richard Jan, Edwards Neil, Savage Robert, Kwentus Joseph, Allen Trina, McEvoy Joseph, Santos Alberto, Gur Raquel, Devlin Bernie, Go Rodney
Abstract excerpt
OBJECTIVE: Various measures of neurocognitive function show mean differences among individuals with schizophrenia (SZ), their relatives, and population controls. We use eigenvector transformations that maximize heritability of multiple neurocognitive measures, namely principal components of heritability (PCH), and evaluate how they distribute in SZ families and controls. METHODS: African-Americans with SZ or...
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