Article
Evidence of shared familial factors influencing neurocognitive endophenotypes in adult- and childhood-onset schizophrenia.
Psychological medicine - 1 Jul 2020
Bigdeli Tim B, Nuechterlein Keith H, Sugar Catherine A, Subotnik Kenneth L, Kubarych Thomas, Neale Michael C, Kendler Kenneth S, Asarnow Robert F
Abstract excerpt
BACKGROUND: The aggregation of neurocognitive deficits among the non-psychotic first-degree relatives of adult- and childhood-onset schizophrenia patients suggests that there may be a common etiology for these deficits in childhood- and adult-onset illness. However, there is considerable heterogeneity in the presentation of neurobiological abnormalities, and whether there are differences in the extent of familial...
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