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Article

Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma.

Cancer research - 1 Jun 2009

Ward Ryan J, Lee Lilian, Graham Kevin, Satkunendran Thevagi, Yoshikawa Koichi, Ling Erick, Harper Lauren, Austin Ryan, Nieuwenhuis Erica, Clarke Ian D, Hui Chi-Chung, Dirks Peter B

Abstract excerpt

Subpopulations of tumorigenic cells have been identified in many human tumors, although these cells may not be very rare in some types of cancer. Here, we report that medulloblastomas arising from Patched-1-deficient mice contain a subpopulation of cells that show a neural precursor phenotype, cl...

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Source

Identifiers

PMID: 19487286
DOI: 10.1158/0008-5472.CAN-09-0342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19487286-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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