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Article

Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.

Stem cells (Dayton, Ohio) - 1 Jun 2008

Shu Qin, Wong Kwong Kwok, Su Jack M, Adesina Adekunle M, Yu Li Tian, Tsang Yvonne T M, Antalffy Barbara C, Baxter Patricia, Perlaky Laszlo, Yang Jianhua, Dauser Robert C, Chintagumpala Murali, Blaney Susan M, Lau Ching C, Li Xiao-Nan

Abstract excerpt

Recent identification of cancer stem cells in medulloblastoma (MB) and high-grade glioma has stimulated an urgent need for animal models that will not only replicate the biology of these tumors, but also preserve their cancer stem cell pool. We hypothesize that direct injection of fresh surgical...

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Identifiers

PMID: 18403755
DOI: 10.1634/stemcells.2007-1009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18403755-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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