Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells

17 Apr 2013

Abstract excerpt

Brain tumors represent the leading cause of childhood cancer mortality, of which medulloblastoma (MB) is the most frequent malignant tumor. Recent studies have demonstrated the presence of several MB molecular subgroups, each distinct in terms of prognosis and predicted therapeutic response. Groups 1 and 2 are characterized by relatively good clinical outcomes and activation of the Wnt and Shh pathways,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23592496
DOI: 10.1002/stem.1401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem CellsPMID 23592496Read ↗

Molecular markers and potential therapeutic targets in non-WNT/non-SHH (group 3 and group 4) medulloblastomasSemantic proximity Read ↗

Dissecting the genomic complexity underlying medulloblastoma.Semantic proximity Read ↗

Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma TreatmentSemantic proximity Read ↗

Medulloblastoma genomics in the modern molecular eraSemantic proximity Read ↗

Molecular Stratification of Medulloblastoma: Clinical Outcomes and Therapeutic Interventions.Semantic proximity Read ↗

Signaling pathway and molecular subgroups of medulloblastoma.Semantic proximity Read ↗

New Approaches in Targeted Therapy for Medulloblastoma in ChildrenSemantic proximity Read ↗

Human stem cell models for group 3 medulloblastoma uncover JARID1B as a regulator of the chromatin landscapeSemantic proximity Read ↗

Signaling pathway deregulation and molecular alterations across pediatric medulloblastomas.Semantic proximity Read ↗

Molecular subgroups of medulloblastoma: the current consensusSemantic proximity Read ↗

Knockdown of Musashi-1 enhances chemotherapeutic sensitivity and apoptosis in Group 3/4 medulloblastomas cellsSemantic proximity Read ↗

Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.