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Article

The Ala allele at Val762Ala polymorphism in poly(ADP-ribose) polymerase-1 (PARP-1) gene is associated with a decreased risk of asthma in a Turkish population.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 May 2009

Tezcan Gulçin, Gurel Cigdem Bayram, Tutluoglu Bulent, Onaran Ilhan, Kanigur-Sultuybek Gonul

Abstract excerpt

BACKGROUND AND OBJECTIVE: It has been suggested that inhibition of poly (ADP-ribose) polymerase-1 (PARP-1), either pharmacologically or by a gene knockout provides significant protection against systemic or tissue inflammation in animal models. The aim of this study was to analyze the association of the PARP-1 Val762Ala polymorphism, which has beenreported to be associated with decreased enzymatic activity, in...

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Identifiers

PMID: 19484672
DOI: 10.1080/02770900902777791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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