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Article

Oxidative damage and DNA damage in lungs of an ovalbumin-induced asthmatic murine model

1 Aug 2018

Abstract excerpt

BACKGROUND: Asthma is characterized to chronic airway inflammation. However, the role of oxidative damage and DNA damage in the pathophysiology of asthma have rarely been studied. On the other hand, there are evidences that DNA-dependent protein kinase (DNA-PK) participates in DNA damage repair and regulates innate immune responses and proinflammatory signaling pathways. METHODS: After ovalbumin (OVA)-induced...

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PMID: 30233855
DOI: 10.21037/jtd.2018.07.74

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