Article
Eyg and Ey Pax proteins act by distinct transcriptional mechanisms in Drosophila development.
The EMBO journal - 20 Jul 2005
Yao Jih-Guang, Sun Y Henry
Abstract excerpt
Drosophila has two pairs of Pax genes, ey/toy and eyg/toe, that play different functions during eye development. ey specifies eye fate, while eyg promotes cell proliferation. We have determined the molecular basis for the functional diversity of Eyg and Ey. Eyg and Ey act by distinct transcriptional mechanisms. They use different DNA-binding domains for target recognition. Most interestingly, Eyg acts exclusively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
