Article
UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 May 2009
Rezvani Khosrow, Teng Yanfen, Pan Yaping, Dani John A, Lindstrom Jon, García Gras Eduardo A, McIntosh J Michael, De Biasi Mariella
Abstract excerpt
Adaptor proteins are likely to modulate spatially and temporally the trafficking of a number of membrane proteins, including neuronal nicotinic acetylcholine receptors (nAChRs). A yeast two-hybrid screen identified a novel UBX-containing protein, UBXD4, as one of the cytosolic proteins that interact directly with the alpha3 and alpha4 nAChR subunits. The function of UBX-containing proteins is largely unknown....
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