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Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone Agents

25 Feb 2020

Abstract excerpt

It is well-established that the spread of many multidrug-resistant (MDR) bacteria is predominantly clonal. Interestingly the international clones/sequence types (STs) of most pathogens emerged and disseminated during the last three decades. Strong experimental evidence from multiple laboratories indicate that diverse fitness cost associated with high-level resistance to fluoroquinolones contributed to the...

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PMID: 32158437
DOI: 10.3389/fmicb.2020.00271

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