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Article

A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism.

BMC systems biology - 27 May 2009

Chu Jen-hwa, Weiss Scott T, Carey Vincent J, Raby Benjamin A

Abstract excerpt

BACKGROUND: Graphical models (e.g., Bayesian networks) have been used frequently to describe complex interaction patterns and dependent structures among genes and other phenotypes. Estimation of such networks has been a challenging problem when the genes considered greatly outnumber the samples, and the situation is exacerbated when one wishes to consider the impact of polymorphisms (SNPs) in genes. RESULTS: Here...

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Identifiers

PMID: 19473523
DOI: 10.1186/1752-0509-3-55
PMCID: PMC2694152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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