Article
SDF1-3' a gene polymorphism is associated with laryngeal cancer.
Pathology oncology research : POR - 1 Jun 2010
Kruszyna Lukasz, Lianeri Margarita, Rydzanicz Małgorzata, Szyfter Krzysztof, Jagodziński Paweł P
Abstract excerpt
The SDF1-3' G801A (rs 1801157) polymorphism is associated with increased risk of various types of cancers, including those of the neck and head. Using PCR-RFLPs, we investigated the distribution of SDF1-3' G801A genotypes in patients with laryngeal cancer (n = 118) and controls (n = 250) in Poland. We found that patients with SDF1-3' A/A and G/A genotypes exhibit a 1.863-fold increased risk of laryngeal cancer...
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