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Article

A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk.

European journal of human genetics : EJHG - 1 Nov 2009

Webb Emily, Broderick Peter, Lubbe Steven, Chandler Ian, Tomlinson Ian, Houlston Richard S

Abstract excerpt

Genome scans based on gene-centric single nucleotide polymorphisms (SNPs) have been proposed as an efficient approach to identify disease-causing variants that is complementary to scans based on tagging SNPs. Adopting this approach to identify low-penetrance susceptibility alleles for colorectal cancer (CRC) we analysed genotype data from 9109 gene-centric SNPs, 7014 of which were non-synonymous (nsSNPs), in 2873...

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Identifiers

PMID: 19471308
DOI: 10.1038/ejhg.2009.92
PMCID: PMC2986682

Genes

MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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