Article
An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics.
Molecular and cellular biology - 1 Aug 2009
Selth Luke A, Lorch Yahli, Ocampo-Hafalla Maria T, Mitter Richard, Shales Michael, Krogan Nevan J, Kornberg Roger D, Svejstrup Jesper Q
Abstract excerpt
The histone chaperone Vps75 forms a complex with, and stimulates the activity of, the histone acetyltransferase Rtt109. However, Vps75 can also be isolated on its own and might therefore possess Rtt109-independent functions. Analysis of epistatic miniarray profiles showed that VPS75 genetically interacts with factors involved in transcription regulation whereas RTT109 clusters with genes linked to DNA...
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