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Article

Autophagy Regulates Ageing in<i>C. elegans</i>

27 Mar 2007

Abstract excerpt

The role of autophagy in ageing regulation has been suggested based on studies in C. elegans, in which knockdown of the expression of bec-1 (ortholog of the yeast and mammalian autophagy genes ATG6/VPS30 and beclin 1, respectively) shortens lifespan of the daf-2(e1370) mutant C. elegans. However, Beclin1/ATG6 is also known to be involved in other cellular functions in addition to autophagy. In the current study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17204841
DOI: 10.4161/auto.3636

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