Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks

23 May 2009

Abstract excerpt

DNA interstrand crosslinks (ICLs) are among the most cytotoxic types of DNA damage, thus ICL-inducing agents such as psoralen, are clinically useful chemotherapeutics. Psoralen-modified triplex-forming oligonucleotides (TFOs) have been used to target ICLs to specific genomic sites to increase the selectivity of these agents. However, how TFO-directed psoralen ICLs (Tdp-ICLs) are recognized and processed in human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Genetic factors in colorectal cancer
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19468048
DOI: 10.1093/nar/gkp399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinksPMID 19468048Read ↗

HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells.Semantic proximity Read ↗

Repair of DNA interstrand cross-links: interactions between homology-dependent and homology-independent pathways.Semantic proximity Read ↗

Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells.Semantic proximity Read ↗

DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase.Semantic proximity Read ↗

Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair.Semantic proximity Read ↗

Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair.Semantic proximity Read ↗

DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy.Semantic proximity Read ↗

The role of BRCA2 in replication-coupled DNA interstrand cross-link repair in vitro.Semantic proximity Read ↗

Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways.Semantic proximity Read ↗

Recruitment and positioning determine the specific role of the XPF-ERCC1 endonuclease in interstrand crosslink repair.Semantic proximity Read ↗

MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.