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Article

The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.

Chemistry & biology - 1 Jun 2006

Arthur Christopher J, Szafranska Anna E, Long Jed, Mills Jane, Cox Russell J, Findlow Stuart C, Simpson Thomas J, Crump Matthew P, Crosby John

Abstract excerpt

Acyl carrier proteins (ACPs) play a fundamental role in directing intermediates among the enzyme active sites of fatty acid and polyketide synthases (PKSs). In this paper, we demonstrate that the Streptomyces coelicolor (S. coelicolor) actinorhodin (act) PKS ACP can catalyze transfer of malonate to type II S. coelicolor fatty acid synthase (FAS) and other PKS ACPs in vitro. The reciprocal transfer from S....

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Source

Identifiers

PMID: 16793516
DOI: 10.1016/j.chembiol.2006.03.010

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The malonyl transferase activity of type II polyketide synthase acyl carrier proteins.PMID 16793516Read ↗

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