Article
Compensatory mutations in the L30e kink-turn RNA-protein complex.
Biochimica et biophysica acta - 1 Jan 2000
Schweppe James J, Jain Chaitanya, White Susan A
Abstract excerpt
The S. cerevisiae ribosomal protein L30e is an autoregulatory protein that binds to its own pre-mRNA and mature mRNA to inhibit splicing and translation, respectively. The L30e RNA-binding element is a stem-asymmetric loop-stem that forms a kink-turn. A bacterial genetic system was designed to test the ability of protein variants to repress the expression of reporter mRNAs containing the L30e RNA-binding element....
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