Article
A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex.
Nature structural biology - 1 Dec 1999
Mao H, White S A, Williamson J R
Abstract excerpt
The yeast Saccharomyces cerevisiae ribosomal protein L30 negatively autoregulates its production by binding to a helix-loop-helix structure formed in its pre-mRNA and its mRNA. A three-dimensional solution structure of the L30 protein in complex with its regulatory RNA has been solved using NMR spectroscopy. In the complex, the helix-loop-helix RNA adopts a sharply bent conformation at the internal loop region....
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