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Article

p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice.

Cancer research - 1 Jun 2009

Schindler Eva M, Hindes Anna, Gribben Erin L, Burns Carole J, Yin Yan, Lin Meei-Hua, Owen Robert J, Longmore Gregory D, Kissling Grace E, Arthur J Simon C, Efimova Tatiana

Abstract excerpt

Activating Ras mutations occur in a large portion of human tumors. Yet, the signaling pathways involved in Ras-induced tumor formation remain incompletely understood. The mitogen-activated protein kinase pathways are among the best studied Ras effector pathways. The p38 mitogen-activated protein kinase isoforms are important regulators of key biological processes including cell proliferation, differentiation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19458068
DOI: 10.1158/0008-5472.CAN-08-4455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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