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Article

Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites.

Biology direct - 20 May 2009

Maurer-Stroh Sebastian, Ma Jianmin, Lee Raphael Tze Chuen, Sirota Fernanda L, Eisenhaber Frank

Abstract excerpt

UNLABELLED: In this work, we study the consequences of sequence variations of the "2009 H1N1" (swine or Mexican flu) influenza A virus strain neuraminidase for drug treatment and vaccination. We find that it is phylogenetically more closely related to European H1N1 swine flu and H5N1 avian flu rather than to the H1N1 counterparts in the Americas. Homology-based 3D structure modeling reveals that the novel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Influenza A Virus, H1N1 Subtype

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Source

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Identifiers

PMID: 19457254
DOI: 10.1186/1745-6150-4-18
PMCID: PMC2691737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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