Article
Theoretical analysis of the neuraminidase epitope of the Mexican A H1N1 influenza strain, and experimental studies on its interaction with rabbit and human hosts.
Immunologic research - 1 May 2013
Loyola Paola Kinara Reyes, Campos-Rodríguez R, Bello Martiniano, Rojas-Hernández S, Zimic Mirko, Quiliano Miguel, Briz Verónica, Muñoz-Fernández M Angeles, Tolentino-López Luis, Correa-Basurto Jose
Abstract excerpt
The neuraminidase (NA) epitope from the Mexican AH1N1 influenza virus was identified by using sequences registered at the GenBank during the peak of a pandemic (from April 2009 to October 2010). First, NA protein sequences were submitted for multiple alignment analysis, and their three-dimensional models (3-D) were then built by using homology modeling. The most common sequence (denominated wild-type) and its...
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