Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer.

Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2012

Sharma Kiran L, Misra Sanjeev, Kumar Ashok, Mittal Balraj

Abstract excerpt

BACKGROUND: Matrix metalloproteinase belong to family of pericellular collagenases which degrade extracellular matrix (ECM), and is involved in the modulation and susceptibility of various cancers. METHODOLOGY: The present study included 410 gallbladder (GBC) cases and 230 healthy controls from North India. Study examined the associations of polymorphisms of MMP-2c.735C>T (rs2285053), MMP-2c.1306 C>T (rs243865),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gallbladder Neoplasms
Share to Logistic Models
Share to Matrix Metalloproteinase 2
Share to Matrix Metalloproteinase 7
Share to Matrix Metalloproteinase 9
Share to Models, Chemical
Share to Multivariate Analysis
Share to Tissue Inhibitor of Metalloproteinase-2

Source

Identifiers

PMID: 22621753
DOI: 10.1111/j.1478-3231.2012.02822.x

Genes

MMP7

Variants

rs243865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher risk of matrix metalloproteinase (MMP-2, 7, 9) and tissue inhibitor of metalloproteinase (TIMP-2) genetic variants to gallbladder cancer.PMID 22621753Read ↗

A multigenic approach to evaluate genetic variants of PLCE1, LXRs, MMPs, TIMP, and CYP genes in gallbladder cancer predisposition.Semantic proximity Read ↗

Functional relevance of MMP2 promoter variants in gallbladder cancer: A case-control study in an Eastern Indian Population.Semantic proximity Read ↗

Genetic association of MMP14 promoter variants and their functional significance in gallbladder cancer pathogenesis.Semantic proximity Read ↗

Matrix metalloproteinase (MMP) -2, -7 and -9 promoter polymorphisms in colorectal cancer in ethnic Kashmiri population - A case-control study and a mini review.Semantic proximity Read ↗

Association between MMP-9 -1562 C/T polymorphism and susceptibility to digestive cancers: A meta-analysis.Semantic proximity Read ↗

Matrix metalloproteinase3 gene promoter polymorphisms and their haplotypes are associated with gastric cancer risk in eastern Indian population.Semantic proximity Read ↗

Current evidence on associations between the MMP-7 (-181A>G) polymorphism and digestive system cancer risk.Semantic proximity Read ↗

Functional polymorphisms of the cyclooxygenase (PTGS2) gene and risk for gallbladder cancer in a North Indian population.Semantic proximity Read ↗

The contribution of the genetic variations of the matrix metalloproteinase-1 gene to the genetic susceptibility of gastric cancer.Semantic proximity Read ↗

Matrix metalloproteinase-1 (MMP-1) Promoter polymorphisms are well linked with lower stomach tumor formation in eastern Indian population.Semantic proximity Read ↗

The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: a meta-analysis.Semantic proximity Read ↗

Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.