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Article

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans.

European journal of clinical pharmacology - 1 Jun 2007

Ghotbi Roza, Christensen Magnus, Roh Hyung-Keun, Ingelman-Sundberg Magnus, Aklillu Eleni, Bertilsson Leif

Abstract excerpt

OBJECTIVES: To investigate the CYP1A2 genotype-phenotype relationship and to compare CYP1A2 genetic polymorphisms and enzyme activity in terms of the effect of smoking and oral contraceptive (OC) use in Swedes and Koreans. METHODS: CYP1A2 enzyme activity was determined in 194 and 150 healthy Swedish and Korean subjects, respectively, on the basis of the 4-h plasma paraxanthine/caffeine (17X/137X) ratio determined...

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PMID: 17370067
DOI: 10.1007/s00228-007-0288-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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