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Article

Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutation.

Muscle & nerve - 1 Apr 2004

Tarnopolsky Mark A, Simon David K, Roy Brian D, Chorneyko Kathy, Lowther Stuart A, Johns Donald R, Sandhu Jagdeep K, Li Yan, Sikorska Marianna

Abstract excerpt

Mitochondrial cytopathies are associated with increased free radical generation and paracrystalline inclusions. Paracrystalline inclusions were serendipitously found in a young male athlete with a very high respiratory exchange ratio during steady-state exercise; he also had an unusually low aerobic capacity. Direct sequencing of the mitochondrial DNA (mtDNA) coding regions revealed a novel missense mutation...

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Identifiers

PMID: 15052619
DOI: 10.1002/mus.20020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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