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Article

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

Nature genetics - 1 Jun 2009

Stolk Lisette, Zhai Guangju, van Meurs Joyce B J, Verbiest Michael M P J, Visser Jenny A, Estrada Karol, Rivadeneira Fernando, Williams Frances M, Cherkas Lynn, Deloukas Panos, Soranzo Nicole, de Keyzer Jules J, Pop Victor J M, Lips Paul, Lebrun Corinne E I, van der Schouw Yvonne T, Grobbee Diederick E, Witteman Jacqueline, Hofman Albert, Pols Huibert A P, Laven Joop S E, Spector Tim D, Uitterlinden André G

Abstract excerpt

We conducted a genome-wide association study for age at natural menopause in 2,979 European women and identified six SNPs in three loci associated with age at natural menopause: chromosome 19q13.4 (rs1172822; -0.4 year per T allele (39%); P = 6.3 × 10(-11)), chromosome 20p12.3 (rs236114; +0.5 year per A allele (21%); P = 9.7 × 10(-11)) and chromosome 13q34 (rs7333181; +0.5 year per A allele (12%); P = 2.5 ×...

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Identifiers

PMID: 19448619
DOI: 10.1038/ng.387
PMCID: PMC3000545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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