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Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity.

DNA repair - 4 Jul 2009

Akbari Mansour, Peña-Diaz Javier, Andersen Sonja, Liabakk Nina-Beate, Otterlei Marit, Krokan Hans Einar

Abstract excerpt

Base excision repair (BER) of damaged or inappropriate bases in DNA has been reported to take place by single nucleotide insertion or through incorporation of several nucleotides, termed short-patch and long-patch repair, respectively. We found that extracts from proliferating and non-proliferating cells both had capacity for single- and two-nucleotide insertion BER activity. However, patch size longer than two...

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Identifiers

PMID: 19442590
DOI: 10.1016/j.dnarep.2009.04.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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