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Article

Cell-type-specific level of DNA nucleotide excision repair in primary human mammary and ovarian epithelial cell cultures.

Cell and tissue research - 1 Sept 2008

Latimer Jean J, Johnson Jennifer M, Miles Tiffany D, Dimsdale Jason M, Edwards Robert P, Kelley Joseph L, Grant Stephen G

Abstract excerpt

DNA repair, a fundamental function of cellular metabolism, has long been presumed to be constitutive and equivalent in all cells. However, we have previously shown that normal levels of nucleotide excision repair (NER) can vary by 20-fold in a tissue-specific pattern. We have now successfully established primary cultures of normal ovarian tissue from seven women by using a novel culture system originally...

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Identifiers

PMID: 18575893
DOI: 10.1007/s00441-008-0645-1
PMCID: PMC4301738

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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