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Article

Decreased Expression of MicroRNA-143 and -145 in Human Gastric Cancers

1 Jan 2009

Abstract excerpt

OBJECTIVE: Downregulation of specific microRNAs (miRNAs) occurs in human tumors, which suggests a function for miRNAs in tumor suppression. We investigated the role of the miRNAs miR-143 and miR-145 in gastric cancers. METHODS: The expression levels of miR-143 and miR-145 in the samples from 43 patients with gastric cancer were determined by real-time PCR using TaqMan assay. The growth inhibitory effect was...

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PMID: 19439999
DOI: 10.1159/000218166

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