Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR‐143 suppresses epithelial–mesenchymal transition and inhibits tumor growth of breast cancer through down‐regulation of ERK5

30 Nov 2015

Abstract excerpt

Epithelial-mesenchymal transition (EMT) plays a pivotal role in the development of cancer invasion and metastasis. Many studies have significantly enhanced the knowledge on EMT through the characterization of microRNAs (miRNAs) influencing the signaling pathways and downstream events that define EMT on a molecular level. In this study, we found that miR-143 suppressed EMT. Up-regulating miR-143 enhanced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26618772
DOI: 10.1002/mc.22445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR‐143 suppresses epithelial–mesenchymal transition and inhibits tumor growth of breast cancer through down‐regulation of ERK5PMID 26618772Read ↗

miR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancerSemantic proximity Read ↗

MiR-93-5p inhibits the EMT of breast cancer cells via targeting MKL-1 and STAT3Semantic proximity Read ↗

miR-503-3p promotes epithelial-mesenchymal transition in breast cancer by directly targeting SMAD2 and E-cadherin.Semantic proximity Read ↗

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in gliomaSemantic proximity Read ↗

Downregulation of microRNA-145 promotes epithelial–mesenchymal transition via regulating Snail in osteosarcomaSemantic proximity Read ↗

53 BP 1 suppresses epithelial–mesenchymal transition by downregulating ZEB 1 through micro RNA ‐200b/429 in breast cancerSemantic proximity Read ↗

miR-506 Regulates Epithelial Mesenchymal Transition in Breast Cancer Cell LinesSemantic proximity Read ↗

microRNA-133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the EGFR/Akt signaling pathway.Semantic proximity Read ↗

E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells.Semantic proximity Read ↗

MiR ‐429 suppresses proliferation and invasion of breast cancer via inhibiting the Wnt/β ‐catenin signaling pathwaySemantic proximity Read ↗

Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasisSemantic proximity Read ↗

Down-Regulation of miR-183 Promotes Migration and Invasion of Osteosarcoma by Targeting EzrinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.