Article
[miR-143 inhibits cell proliferation through targeted regulating the expression of K-ras gene in HeLa cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Dec 2016
Qin H X, Cui H K, Pan Y, Hu R L, Zhu L H, Wang S J
Abstract excerpt
Objective: To explore the effect of microRNA miR-143 on the proliferation of cervical cancer HeLa cells through targeted regulating the expression of K-ras gene. Methods: The luciferase report carrier containing wild type 3'-UTR of K-ras gene (K-ras-wt) or mutated 3'-UTR of the K-ras (K-ras-mut) were co-transfected with iR-143 mimic into the HeLa cells respectively, and the targeting effect of miR-143 in the...
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