Article
MicroRNA-143 suppresses gastric cancer cell growth and induces apoptosis by targeting COX-2.
World journal of gastroenterology - 1 Jan 2013
Wu Xiao-Li, Cheng Bin, Li Pei-Yuan, Huang Huan-Jun, Zhao Qiu, Dan Zi-Li, Tian De-An, Zhang Peng
Abstract excerpt
AIM: To investigate the function of microRNA-143 (miR-143) in gastric cancer and explore the target genes of miR-143. METHODS: A quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) analysis was performed to evaluate miR-143 expression in gastric cancer cell lines. After transfecting gastric cancer cells with miR-143-5p and miR-143-3p precursors, Alamar blue and apoptosis assays were...
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