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Article

Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2.

Journal of cellular and molecular medicine - 1 Sept 2009

Mirmalek-Sani Sayed-Hadi, Stokes Paula J, Tare Rahul S, Ralph Esther J, Inglis Stefanie, Hanley Neil A, Houghton Franchesca D, Oreffo Richard O C

Abstract excerpt

Skeletal stem and progenitor populations provide a platform for cell-based tissue regeneration strategies. Optimized conditions for ex vivo expansion will be critical and use of serum-free culture may allow enhanced modelling of differentiation potential. Maintenance of human foetal femur-derived cells in a chemically defined medium (CDM) with activin A and fibroblast growth factor-2 generated a unique...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19438813
DOI: 10.1111/j.1582-4934.2009.00742.x
PMCID: PMC3430854

Genes

CLU
CRYAB
CSRP1
DUSP6
EPAS1
GFPT2
GREM1
HMGCS1
OSR2
POSTN
PPL
RABGAP1
SOX15
SQLE
SRGN
WIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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