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Article

In vitro direct osteogenesis of murine embryonic stem cells without embryoid body formation.

Stem cells and development - 1 Oct 2008

Hwang Yu-Shik, Polak Julia M, Mantalaris Athanasios

Abstract excerpt

Embryonic stem cells (ESCs) posses the ability to self-renew and differentiate into a multitude of lineages, including the osteogenic lineage in vitro. Currently, most approaches have focused on embryonic body (EB)-mediated osteogenic differentiation, which relies on formation of all three germ layers resulting in limited yields and labour-intensive culture processes. Our study aimed at developing an efficient...

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Identifiers

PMID: 18564030
DOI: 10.1089/scd.2007.0228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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