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Potential of Human Fetal Chorionic Stem Cells for the Treatment of Osteogenesis Imperfecta

12 Sept 2013

Abstract excerpt

Osteogenesis imperfecta (OI) is a genetic bone pathology with prenatal onset, characterized by brittle bones in response to abnormal collagen composition. There is presently no cure for OI. We previously showed that human first trimester fetal blood mesenchymal stem cells (MSCs) transplanted into a murine OI model (oim mice) improved the phenotype. However, the clinical use of fetal MSC is constrained by their...

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PMID: 24028330
DOI: 10.1089/scd.2013.0132

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