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Development and characterization of a clinically compliant xeno-free culture medium in good manufacturing practice for human multipotent mesenchymal stem cells.

Stem cells translational medicine - 1 Oct 2012

Chase Lucas G, Yang Sufang, Zachar Vladimir, Yang Zheng, Lakshmipathy Uma, Bradford Jolene, Boucher Shayne E, Vemuri Mohan C

Abstract excerpt

Human multipotent mesenchymal stem cell (MSC) therapies are currently being tested in clinical trials for Crohn's disease, multiple sclerosis, graft-versus-host disease, type 1 diabetes, bone fractures, cartilage damage, and cardiac diseases. Despite remarkable progress in clinical trials, most applications still use traditional culture media containing fetal bovine serum or serum-free media that contain serum...

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Identifiers

PMID: 23197667
DOI: 10.5966/sctm.2012-0072
PMCID: PMC3659659

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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