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Article

Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium.

Molecular human reproduction - 22 Jan 2021

Marla S, Mortlock S, Houshdaran S, Fung J, McKinnon B, Holdsworth-Carson S J, Girling J E, Rogers P A W, Giudice L C, Montgomery G W

Abstract excerpt

The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) region associated with endometriosis and other reproductive traits and diseases. In addition, candidate gene association studies identified signals in the ESR1 region associated...

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Identifiers

PMID: 33394050
DOI: 10.1093/molehr/gaaa082
PMCID: PMC8453628

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