Article
A comparative study of five nitro musk compounds for genotoxicity in the SOS chromotest and Salmonella mutagenicity.
Toxicology letters - 1 Jun 1996
Emig M, Reinhardt A, Mersch-Sundermann V
Abstract excerpt
Five nitro musk compounds widely used in cosmetics and detergents were examined for DNA-damaging and mutation-inducing properties. For this purpose two short-time assays were used, the SOS chromotest and the Salmonella/mammalian microsome test. Musk ambrette showed mutagenicity in Salmonella typh...
Topics
- Alkaline Phosphatase
- Animals
- Aroclors
- Biotransformation
- Carcinogens
- Chlorodiphenyl (54% Chlorine)
- DNA Damage
- Dinitrobenzenes
- Dose-Response Relationship, Drug
- Escherichia coli
- Indans
- Mitochondria, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Perfume
- Rats
- SOS Response, Genetics