Article
The mutagenicity on Salmonella typhimurium of nitrobenzoic acids and other wastewater components generated in the production of nitrobenzoic acids and nitrotoluenes.
Mutation research - 1 Jan 2000
Sundvall A, Marklund H, Rannug U
Abstract excerpt
The wastewater contained mutagens which induced mutations in Salmonella typhimurium TA1535, TA1538, TA98 and TA100. By the use of nitroreductase-proficient and -deficient tester strains, it was possible to demonstrate that the mutagens were to a great extent aromatic nitro compounds. 30-40% of th...
Topics
- Animals
- Biotransformation
- Male
- Microsomes, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Nitrobenzoates
- Rats
- Rats, Inbred Strains
- Salmonella typhimurium
- Sewage
- Species Specificity
- Structure-Activity Relationship
- Toluene
- Waste Disposal, Fluid
- Water Pollutants
- Water Pollutants, Chemical