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Article

Antigenotoxic properties of two newly synthesized β-aminoketones against N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine-induced mutagenesis.

Journal of biochemical and molecular toxicology - 1 Jul 2012

Ozturkcan S Arda, Turhan Kadir, Turgut Zuhal, Karadayi Mehmet, Gulluce Medine

Abstract excerpt

The aim of this study was to determine the antigenotoxic potential of two newly synthesized β-aminoketones against N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 9-aminoacridine (9-AA)-induced mutagenesis. The mutant bacterial tester strains were MNNG-sensitive Escherichia coli WP2 uvrA and 9-AA-sensitive Salmonella typhimurium TA1537. Both test compounds showed significant antimutagenic activity at various...

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PMID: 22645030
DOI: 10.1002/jbt.21414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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