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Article

The clinical significance of K-ras mutation in endometrial "surface epithelial changes" and their associated endometrial adenocarcinoma.

Gynecologic oncology - 1 Jul 2016

Xiong Jinjun, He Mai, Hansen Katrine, Jackson Cynthia L, Breese Virginia, Quddus M Ruhul, Sung C James, Lomme Michele M, Lawrence W Dwayne

Abstract excerpt

OBJECTIVES: The entity of 'surface epithelial changes' (SECs) was first described in 1995 [1]. Morphologically, SECs usually arise from malignant glands at the superficial aspect of well differentiated (WD) endometrioid carcinomas (ECs) and impart the appearance of a 'maturational' phenomenon at the surface of the cancer. Exhibiting a paradoxically bland histologic appearance, SECs typically show morphologic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins p21(ras)

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Identifiers

PMID: 27154241
DOI: 10.1016/j.ygyno.2016.05.001

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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