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Article

Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations.

Gynecologic oncology - 1 Nov 2008

Saleemuddin Aasia, Folkins Ann K, Garrett Leslie, Garber Judy, Muto Michael G, Crum Christopher P, Tworoger Shelley

Abstract excerpt

OBJECTIVES: Pelvic (ovarian) serous carcinomas frequently contain p53 mutations. Recently, a candidate serous cancer precursor (the p53 signature) with p53 mutations and other features in common with serous cancer has been discovered in distal fallopian tube mucosa. This study examined the relationship of putative ovarian cancer risk factors with the presence of p53 signatures in women with BRCA mutations...

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Share to Cystadenocarcinoma, Serous
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

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Share to Ovarian Neoplasms

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 18718648
DOI: 10.1016/j.ygyno.2008.07.018
PMCID: PMC2613977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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