Article
Imprinting analysis in the Acrodysplasia region of mouse chromosome 12.
Bioscience reports - 23 Nov 2009
McMurray Erin N, Rogers Eric D, Schmidt Jennifer V
Abstract excerpt
The insertional mouse mutation Adp (Acrodysplasia) confers a parent-of-origin developmental phenotype, with animals inheriting the mutation from their father showing skeletal abnormalities, whereas those inheriting the mutation from their mother are normal. This parental-specific phenotype, along with mapping of the insertion to a region of chromosome 12 proposed to contain imprinted genes, suggested that...
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