Article
A cluster of oppositely imprinted transcripts at the <i>Gnas</i> locus in the distal imprinting region of mouse chromosome 2
30 Mar 1999
Abstract excerpt
Imprinted genes tend to occur in clusters. We have identified a cluster in distal mouse chromosome (Chr) 2, known from early genetic studies to contain both maternally and paternally imprinted, but unspecified, genes. Subsequently, one was identified as Gnas, which encodes a G protein alpha subunit, and there is clinical and biochemical evidence that the human homologue GNAS1, mutated in patients with Albright...
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