Article
Control of imprinting at the Gnas cluster.
Epigenetics - 1 Jan 2000
Peters Jo, Williamson Christine M
Abstract excerpt
Genomic imprinting is a form of epigenetic regulation in mammals whereby a small subset of genes is silenced according to parental origin. Early work had indicated regions of the genome that were likely to contain imprinted genes. Distal mouse chromosome 2 is one such region and is associated with devastating but ostensibly opposite phenotypes when exclusively maternally or paternally derived. Misexpression of...
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