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Article

Myofilament incorporation determines the stoichiometry of troponin I in transgenic expression and the rescue of a null mutation.

Archives of biochemistry and biophysics - 1 Jul 2009

Feng Han-Zhong, Hossain M Moazzem, Huang Xu-Pei, Jin J-P

Abstract excerpt

The highly organized contractile machinery in skeletal and cardiac muscles requires an assembly of myofilament proteins with stringent stoichiometry. To understand the maintenance of myofilament protein stoichiometry under dynamic protein synthesis and catabolism in muscle cells, we investigated the equilibrium of troponin I (TnI) in mouse cardiac muscle during developmental isoform switching and in under- and...

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Identifiers

PMID: 19433057
DOI: 10.1016/j.abb.2009.05.001
PMCID: PMC2752407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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