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Article

p53 tumour suppressor gene polymorphism is associated with recurrent implantation failure.

Reproductive biomedicine online - 1 Oct 2006

Kay C, Jeyendran R S, Coulam C B

Abstract excerpt

Implantation failure is the most frequent cause of lack of pregnancy after IVF and embryo transfer. Successful implantation requires trophoblastic growth into the endometrium to stimulate its own blood supply. The p53 tumour suppressor gene has been shown to regulate cell growth and induce angiogenesis. Therefore, the prevalence of p53 codon 72 polymorphism was investigated among women with a history of recurrent...

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Identifiers

PMID: 17007666
DOI: 10.1016/s1472-6483(10)60635-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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