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Article

Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis.

Mutation research - 12 May 2009

Khan Anwar Jamal, Ruwali Munindra, Choudhuri Gourdas, Mathur Neeraj, Husain Qayyum, Parmar Devendra

Abstract excerpt

The association of polymorphism in cytochrome P450 2E1 (CYP2E1), the major microsomal ethanol metabolizing enzyme and its interaction with genes, involved in detoxification of reactive oxygen species, such as glutathione-S-transferases M1 (GSTM1) and alcohol intake, gamma-aminobutyric acid receptor gamma2 (GABRG2) was studied with the risk to alcoholic cirrhosis in a case-control study. A total of 160 alcoholic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Liver Cirrhosis

Share to Liver Cirrhosis, Alcoholic

Share to Odds Ratio

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, GABA-A

Source

Identifiers

PMID: 19428381
DOI: 10.1016/j.mrfmmm.2009.02.009

Genes

GABRG2
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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