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Article

Genetic Association and Gene-Gene Interaction Reveal Genetic Variations in ADH1B, GSTM1 and MnSOD Independently Confer Risk to Alcoholic Liver Diseases in India.

PloS one - 1 Jan 2016

Roy Neelanjana, Dasgupta Debanjali, Mukhopadhyay Indranil, Chatterjee Ankita, Das Kausik, Bhowmik Pradip, Das Soumyajit, Basu Priyadarshi, Santra Amal K, Datta Simanti, Dhali Gopal Krishna, Chowdhury Abhijit, Banerjee Soma

Abstract excerpt

Genetic susceptibility is an important modifier of clinical outcome and natural history of progression in Alcoholic liver disease (ALD). While the significance of ethnicity in this evolution is very clear, subtle inter-individual genetic variant(s) might be important and thus we investigated those in an Indian population. Fourteen markers were genotyped within two alcohol metabolism genes [Alcohol dehydrogenase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26937962
DOI: 10.1371/journal.pone.0149843
PMCID: PMC4777485

Genes

GSTM1
GSTT1
ALDH2

Provenance

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