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Article

Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice.

Biochemical and biophysical research communications - 10 Jul 2009

Lee Junghee, Ryu Hoon, Kowall Neil W

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive paralysis due to motor neuron degeneration. Despite the fact that many different therapeutic strategies have been applied to prevent disease progression, no cure or effective therapy is currently available for ALS. We found that L-arginine protects cultured motor neurons from excitotoxic injury. We also found...

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Identifiers

PMID: 19427829
DOI: 10.1016/j.bbrc.2009.05.015
PMCID: PMC2744197

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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